Analysis of viral genetic data has previously revealed distinct within-host population structures in both untreated and interferon-treated chronic hepatitis C virus (HCV) infections.While multiple subpopulations persisted during the infection, each subpopulation was observed only intermittently.However, it was unknown whether similar patterns were
Microzooplankton (MZP) are an important part of the microbial food web and play a pivotal role in connecting the classic food chain with the microbial loop in the marine ecosystem.They may play a more important role than mesozooplankton in the lower latitudes and oligotrophic oceans.In this article, we studied the species composition, dominant spec
The left atrial appendage (LAA) is a complex cardiovascular structure which can yield to thrombi formation in patients with non-valvular atrial fibrillation (AF).The study of LAA fluid dynamics together with morphological features should be investigated in order to evaluate the possible connection of geometrical and hemodynamics indices with the Sc
Effective implementation of cancer screening programs can reduce disease-specific incidence and mortality.Screening is currently recommended for breast, cervical, colorectal and lung cancer.However, initial and repeat adherence to screening tests in accordance with current guidelines is sub-optimal, with the lowest rates observed in historically un
Abstract Background A prerequisite for the mechanistic simulation of a biochemical system is detailed knowledge of its kinetic parameters.Despite recent experimental advances, the estimation of unknown parameter values from observed data is still a bottleneck for obtaining accurate simulation results.Many methods exist for parameter estimation in d